Factor B Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.
Synonyms
BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14; Complement factor B; C3/C5 convertase; Glycine-rich beta glycoprotein; Properdin factor B; CFB
Gene ID
629
Swiss Prot
P00751
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
301-400/764
Target
Factor B
Clonality
Polyclonal
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human Complement factor-B Bb fragment
Applications
WB, ELISA, IHC-P
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
629
Isotype
IgG
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