CHAC1 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade.
Synonyms
Cation transport regulator-like protein 1; Blocks Notch protein; Botch; CHAC1
Gene ID
79094
Swiss Prot
Q9BUX1
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
131-264/264
Target
CHAC1
Clonality
Polyclonal
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human CHAC1
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Human, Dog, Cow, Pig, Rabbit
Gene ID URL
79094
Isotype
IgG
Curated Selection
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