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GIRK1/KCNJ3 Polyclonal Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

Synonyms

KGA; GIRK1; KIR3.1; G protein-activated inward rectifier potassium channel 1; GIRK-1; Inward rectifier K (+) channel Kir3.1; Potassium channel, inwardly rectifying subfamily J member 3; KCNJ3

Gene ID

3760

Swiss Prot

P48549

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

81-180/501

Target

GIRK1/KCNJ3

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic peptide derived from human GIRK1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Dog, Cow, Pig, Rabbit, GuineaPig

Gene ID URL

3760

Isotype

IgG

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