HRH2 Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway (By similarity) .
Synonyms
H2R; Histamine H2 receptor; HH2R; Gastric receptor I; HRH2
Gene ID
3274
Swiss Prot
P25021
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
161-259/359
Target
HRH2
Clonality
Polyclonal
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human HRH2
Applications
WB, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (WB=1:500-2000), IHC-P (IHC-P=1:100-500), IHC-F (IHC-F=1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Rat, Dog, Rabbit
Gene ID URL
3274
Isotype
IgG
Curated Selection
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