TYK2 Polyclonal Antibody, PE-Cy5 Conjugated
Product Specifications
Background
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].
Synonyms
JTK 1; JTK1; Non receptor tyrosine protein kinase 2; Non receptor tyrosine protein kinase TYK2; Non-receptor tyrosine-protein kinase TYK2; Protein Tyrosine Kinase 2; TYK 2; Tyk2; TYK2_HUMAN; Tyrosine kinase 2.
Gene ID
7297
Cellular Locus
Cytoplasm, Nucleus, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human
Immunogen
401-500/1178
Target
TYK2
Clonality
Polyclonal
Conjugation
PE-Cy5
Source
KLH conjugated synthetic peptide derived from human TYK2
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
1ug/ul
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit, GuineaPig
Gene ID URL
7297
Isotype
IgG
Curated Selection
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