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TYK2 Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].

Synonyms

JTK 1; JTK1; Non receptor tyrosine protein kinase 2; Non receptor tyrosine protein kinase TYK2; Non-receptor tyrosine-protein kinase TYK2; Protein Tyrosine Kinase 2; TYK 2; Tyk2; TYK2_HUMAN; Tyrosine kinase 2.

Gene ID

7297

Cellular Locus

Cytoplasm, Nucleus, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human

Immunogen

401-500/1178

Target

TYK2

Clonality

Polyclonal

Conjugation

Biotin

Source

KLH conjugated synthetic peptide derived from human TYK2

Applications

WB, ELISA

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C for 12 months.

Prediction Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit, GuineaPig

Gene ID URL

7297

Isotype

IgG

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