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ADORA1 Polyclonal Antibody, AbBy Fluor™ 647 Conjugated

Product Specifications

Background

Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNF?and blocks the endotoxin CD14 receptor signal transduction pathway.

Synonyms

RDC7; Adenosine receptor A1; ADORA1

Gene ID

134

Swiss Prot

P30542

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

225-326/326

Target

ADORA1

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 647

Source

KLH conjugated synthetic peptide derived from human Adenosine A1 Receptor

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

650nm/665nm

Concentration

1ug/ul

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Dog, Cow, Pig, Horse, Chicken, Rabbit

Gene ID URL

134

Isotype

IgG

Curated Selection

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