PAPPA Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.

Synonyms

PAPA; DIPLA1; PAPP-A; PAPPA1; ASBABP2; IGFBP-4ase; Pappalysin-1; Insulin-like growth factor-dependent IGF-binding protein 4 protease; IGF-dependent IGFBP-4 protease; Pregnancy-associated plasma protein A; PAPPA

Gene ID

5069

Swiss Prot

Q13219

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

1321-1460/1627

Target

PAPPA

Clonality

Polyclonal

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human PAPPA

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1ug/ul

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Rat, Dog, Cow, Pig, Horse, Rabbit

Gene ID URL

5069

Isotype

IgG

Curated Selection

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