PAPPA Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.
Synonyms
PAPA; DIPLA1; PAPP-A; PAPPA1; ASBABP2; IGFBP-4ase; Pappalysin-1; Insulin-like growth factor-dependent IGF-binding protein 4 protease; IGF-dependent IGFBP-4 protease; Pregnancy-associated plasma protein A; PAPPA
Gene ID
5069
Swiss Prot
Q13219
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
1321-1460/1627
Target
PAPPA
Clonality
Polyclonal
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human PAPPA
Applications
ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Human, Rat, Dog, Cow, Pig, Horse, Rabbit
Gene ID URL
5069
Isotype
IgG
Curated Selection
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