FbpB Polyclonal Antibody
Product Specifications
Background
The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein, which facilitates the attachment of M.tuberculosis to murine alveolar macrophages (AMs) . They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha, alpha-trehalose dimycolate (TDM, cord factor) . They catalyze the transfer of a mycoloyl residue from one molecule of alpha, alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM
Synonyms
M.tuberculosis; Antigen 85 complex B;30 kDa extracellular protein; Mycobacterium; Mycolyl transferase 85B; A85B_MYCTU; Antigen 85-B; 30 kDa extracellular protein; 85B; Ag85B; Extracellular alpha-antigen; Fibronectin-binding protein B.
Gene ID
885785, 886132
Swiss Prot
P9WQP1, P9WQP3
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Bacteria
Immunogen
115-154/325
Target
FbpB
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Antigen 85 complex B
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Specificity
This antibody will detect both Mycobacterium tuberculosis Ag85A and Mycobacterium tuberculosis Ag85B
Gene ID URL
885785, 886132
Isotype
IgG
Curated Selection
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