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4 Hydroxynonenal Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Aldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress 4-HNE has been hypothesized to play a key role in cell signal transduction, in a variety of pathways from cell cycle events to cellular adhesion.

Synonyms

4-Hydroxy-2-Nonenal; 4Hydroxynonenal; 4-Hydroxynonenal; 4 HNE; 4HNE; 4-HNE; E-4-Hydroxynonenal-dimethylacetal, 4-HNE-DMA.

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Others

Target

4 Hydroxynonenal

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 405

Source

KLH-conjugated 4-hydroxynonenal

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Isotype

IgG

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