EMP2 Polyclonal Antibody, PerCP Conjugated
Product Specifications
Background
EMP-2 is a 167 amino acid multi-pass membrane protein that contains four-transmembrane domains and belongs to the GAS3/PMP22 (growth arrest-specific-3/peripheral myelin protein-22) family. Localized to lipid raft domains in the plasma membrane, EMP-2 regulates the expression of several target proteins and is necessary for blastocyst implantation in the uterine endometrium. Specifically, EMP-2 mediates blastocyst implantation by controlling the cell membrane expression of MHC and glycosylphosphatidylinositol-anchored proteins, as well as Integrins and caveolin-1. In adult tissues, EMP-2 is expressed in heart, lung, ovary and intestine, while fetal expression is highest in kidney, brain and liver. Overexpression of EMP-2 is associated with endometrial adenocarcinoma, suggesting a possible role for EMP-2 in tumorigenesis.
Synonyms
EMP-2; EMP2; EMP2_HUMAN; Epithelial membrane protein 2; Protein XMP.
Gene ID
2013
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
65-167/167
Target
EMP2
Clonality
Polyclonal
Conjugation
PerCP
Source
KLH conjugated synthetic peptide derived from human EMP2
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
482nm/677nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Human, Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Gene ID URL
2013
Isotype
IgG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb505744 100 µL
Phospho-Cardiac Troponin I (Ser23 + Ser24) Rabbit Polyclonal Antibody (PE)
Sign In for Pricing
View Details 
MBS1408209 Inquire
Recombinant Streptococcus mutans UvrABC system protein C (uvrC), partial
Sign In for Pricing
View Details 