IMPDH1 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP) . This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10) . Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
Synonyms
IMDH1_HUMAN; IMP inosine monophosphate dehydrogenase 1; IMP dehydrogenase 1; IMPD 1; IMPD; IMPD1; IMPDH 1; IMPDH I; IMPDH-I; Impdh1; Inosine 5' monophosphate dehydrogenase 1; Inosine monophosphate dehydrogenase 1; Inosine-5''-monophosphate dehydrogenase 1; Inosine-5'-monophosphate dehydrogenase 1; LCA11; RP10.
Gene ID
3614
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
201-300/514
Target
IMPDH1
Clonality
Polyclonal
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human IMPDH1
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Prediction Reactivity
Dog, Cow, Pig, Rabbit, GuineaPig
Gene ID URL
3614
Isotype
IgG
Curated Selection
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