KLK8 Polyclonal Antibody, AbBy Fluor™ 350 Conjugated
Product Specifications
Background
Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.
Synonyms
BSP1; Nrpn; Prss19; Kallikrein-8; mK8; Neuropsin; NP; Serine protease 19; Klk8
Gene ID
259277
Swiss Prot
Q61955
Cellular Locus
Cytoplasm, Secreted
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
51-150/260
Target
KLK8
Clonality
Polyclonal
Conjugation
AbBy Fluor™ 350
Source
KLH conjugated synthetic peptide derived from mouse KLK8
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
346nm/442nm
Concentration
1ug/ul
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Human, Dog, Cow, Pig, Horse, GuineaPig
Gene ID URL
259277
Isotype
IgG
Curated Selection
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