Phospho-NFKB p65 (Thr505) Polyclonal Antibody, AbBy Fluor™ 555 Conjugated
Selected Variant
bs-5663R-BF555-TR
Size: 20 µL
Product Specifications
Background
NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011].
Synonyms
NF B-p65 Thr505; NF B-p65 Thr505; RELAphospho T505; NFKBp65; NF-Bp65; p65 NF kappaB; p65 NFkB; NFKBp65; RELA; Transcription Factor p65; v rel avian reticuloendotheliosis viral oncogene homolog A nuclear factor of kappa light polypeptide gene enhancer in B cells 3 p65; V Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A; v rel reticuloendotheliosis viral oncogene homolog A avian; v-rel reticuloendotheliosis viral oncogene homolog A; p65NFKB; Avian reticuloendotheliosis viral v rel oncogene homolog A; MGC131774; NFKB 3; NFKB3; Nuclear Factor NF Kappa B p65 Subunit; Nuclear factor of kappa light polypeptide gene enhancer in B cells 3; Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B Cells.
Gene ID
5970
Modification Site
Thr505
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Phospho-NFKB p65 (Thr505)
Clonality
Polyclonal
Conjugation
AbBy Fluor™ 555
Source
KLH conjugated synthetic phosphopeptide derived from human c-Raf around the phosphorylation site of Ser301
Applications
WB
Purification
Purified by Protein A.
Excitation Emission
553nm/568nm
Concentration
1ug/ul
Dilution
WB (1:300-5000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Rat, Dog, Cow, Pig
Gene ID URL
5970
Isotype
IgG
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