Ac-rC Phosphoramidite

Ac-rC Phosphoramidite is a phosphoramidite containing 5’ DMT and the nucleoside cytiding with Acetyl base protection. Ac-rC Phosphoramidite is used for the oligoribonucleotide phosphorodithioate modification (PS2-RNA) [1].

Product Specifications

CAS Number

[121058-88-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DNA/RNA Synthesis

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-rc-phosphoramidite.html

Purity

98.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H](N5C(N=C(NC(C)=O)C=C5)=O)O4

Molecular Formula

C47H64N5O9PSi

Molecular Weight

902.10

Precautions

H302, H315, H319, H335

References & Citations

[1]Wipapat Kladwang, et al. Anomalous Reverse Transcription through Chemical Modifications in Polyadenosine Stretches. Biochemistry. 2020 Jun 16;59 (23) :2154-2170.