Ceramide synthase 2 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

LASS2 (LAG1 homolog, ceramide synthase 2) has sequence similarity to yeast longevity assurance gene 1. It is thought to be involved in sphingolipid synthesis. Expression of LASS2 is transiently increased during the period of active myelination and is specifically localized to white matter tracts of the brain, including the Schwann cells of sciatic nerves suggesting that LASS2 is important for the synthesis of dihydroceramide used for synthesis of myelin sphingolipids. Expression of LASS2 in hepatocellular carcinoma cell lines suppresses the growth of cancer cells.

Synonyms

L3; LASS2; SP260; TMSG1; Ceramide synthase 2; CerS2; LAG1 longevity assurance homolog 2; Tumor metastasis-suppressor gene 1 protein

Gene ID

29956

Swiss Prot

Q96G23

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

201-300/380

Target

Ceramide synthase 2

Clonality

Polyclonal

Conjugation

Source

KLH conjugated synthetic peptide derived from human Ceramide synthase 2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Mouse, Cow, Pig, Horse, Chicken, Rabbit

Gene ID URL

29956

Isotype

IgG

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