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SORBS2 Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1 or with AKT1 and PAK1, thus mediating AKT1-mediated activation of PAK1. Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.

Synonyms

ARGBP2; PRO618; Sorbin and SH3 domain-containing protein 2; Arg/Abl-interacting protein 2; Sorbin; SORBS2; KIAA777

Gene ID

8470

Swiss Prot

O94875

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

401-500/664

Target

SORBS2

Clonality

Polyclonal

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human SORBS2/ArgBP2

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Dog, Pig, Horse, Chicken, Rabbit

Gene ID URL

8470

Isotype

IgG

Curated Selection

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