Etilefrine
Product Specifications
UNSPSC Description
Etilefrine (3-[2-(ethylamino)-1-hydroxyethyl]phenol) is an α adrenergic agonist[2]. Etilefrine also is an AMPK activator[1]. Etilefrine can be used for the research of postural hypotension[3].
Target Antigen
Adrenergic Receptor; AMPK
Type
Reference compound
Related Pathways
Epigenetics;GPCR/G Protein;Neuronal Signaling;PI3K/Akt/mTOR
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/etilefrine.html
Purity
97.03
Solubility
DMSO : 40 mg/mL (ultrasonic)
Smiles
OC(CNCC)C1=CC=CC(O)=C1
Molecular Weight
181.23
References & Citations
[1]Sylvain Tollis, et al. Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion. ACS Chem Biol. 2022 Feb 24.|[2]Chi Xu, et al. Accurate Drug Repositioning through Non-tissue-Specific Core Signatures from Cancer Transcriptomes. Cell Rep. 2018 Oct 9;25(2):523-535.e5.|[3]R Yamazaki, et al. Effects of dihydroergotamine and Etilefrine on experimentally-induced postural hypotension in dogs. J Pharmacobiodyn. 1990 Sep;13(9):519-24.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-A0144/Etilefrine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-A0144/Etilefrine-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
709-55-7
Available Sizes
Curated Selection
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