Synaptotagmin 1 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca (2+) -dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca (2+) -independent manner; these are neurexins, syntaxin and AP2.
Synonyms
P65; SYT; SVP65; Synaptotagmin-1; Synaptotagmin I; SytI; SYT1
Gene ID
6857
Swiss Prot
P21579
Cellular Locus
Secreted, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
165-260/422
Target
Synaptotagmin 1
Clonality
Polyclonal
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human Synaptotagmin 1
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This antibody will cross-react with Synaptotagmin 2 and
Prediction Reactivity
Dog, Cow, Pig, Chicken, Rabbit
Gene ID URL
6857
Isotype
IgG
Curated Selection
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