FBP1 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Synonyms
FBP; Fructose-1,6-bisphosphatase 1; FBPase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; Liver FBPase; FBP1
Gene ID
2203
Swiss Prot
P09467
Cellular Locus
Cytoplasm, Nucleus, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
31-130/338
Target
FBP1
Clonality
Polyclonal
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human FBP1
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Prediction Reactivity
Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit
Gene ID URL
2203
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
KBH16651 1x 96 Well
GENLISA Human T-Cell Immunoreceptor With Ig And Itim Domains Protein (TIGIT) ELISA
Ask
View Details 
GTR15249135 1 Vial
Lentiviral mouse E330021D16Rik shRNA (UAS) - Lentiviral mouse E330021D16Rik shRNA (UAS, iRFP) (100)
Ask
View Details 
MBS1158447-01 0.02 mg (E-Coli)
Recombinant Shigella flexneri Arsenate reductase (arsC)
Ask
View Details