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CYP24A1 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Has a role in maintaining calcium homeostasis. Catalyzes the NADPH-dependent 24-hydroxylation of calcidiol (25-hydroxyvitamin D (3) ) and calcitriol (1-alpha,25-dihydroxyvitamin D (3) ) . The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23-hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D (3) -26,23-lactone as end product.

Synonyms

CP24; HCAI; CYP24; P450-CC24; 1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial; 24-OHase; Vitamin D (3) 24-hydroxylase; Cytochrome P450 24A1; Cytochrome P450-CC24; CYP24A1

Gene ID

1591

Swiss Prot

Q07973

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

351-450/514

Target

CYP24A1

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human CYP24A1

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1ug/ul

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Dog, Cow, Pig, Horse, Chicken, Rabbit

Gene ID URL

1591

Isotype

IgG

Curated Selection

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