PPAR alpha Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC) . Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

Synonyms

PPAR; NR1C1; hPPAR; PPARalpha; Peroxisome proliferator-activated receptor alpha; PPAR-alpha; Nuclear receptor subfamily 1 group C member 1; PPARA

Gene ID

5465

Swiss Prot

Q07869

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

301-400/468

Target

PPAR alpha

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from human PPAR alpha

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Cow, Pig, Horse, Chicken, Rabbit

Gene ID URL

5465

Isotype

IgG

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SC332934 10 µg

RTBDN (NM_001270442) Human Untagged Clone

Ask

View Details

ABC-KD1335 1 Vial

Human BARHL2 knockdown cell line

Ask

View Details

QH24969S 200 Tests

Human ZNF708 qPCR Primer Pair

Ask

View Details

SC319416 10 µg

IL11RA (NM_004512) Human Untagged Clone

Ask

View Details

MR221801L3V 200 µL

Olfr596 (NM_001190381) Mouse Tagged ORF Clone Lentiviral Particle

Ask

View Details

MBS1175115-01 0.02 mg (E-Coli)

Recombinant Streptococcus suis (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase

Ask

View Details