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HBEGF Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.

Synonyms

DTR; DTS; DTSF; HEGFL; Proheparin-binding EGF-like growth factor; HBEGF

Gene ID

1839

Swiss Prot

Q99075

Cellular Locus

Secreted, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

51-150/208

Target

HBEGF

Clonality

Polyclonal

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human HB-EGF/DTSF

Applications

IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1ug/ul

Dilution

IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit

Gene ID URL

1839

Isotype

IgG

Curated Selection

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