Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Phospho-Stat2 (Tyr690) Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) . Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Synonyms

P113; ISGF-3; STAT113; Signal transducer and activator of transcription 2; STAT2

Gene ID

6773

Swiss Prot

P52630

Modification Site

Tyr690

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Target

Phospho-Stat2 (Tyr690)

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous to that of Tyr689 in Mouse and Tyr690 in Rat.

Prediction Reactivity

Human, Rat, Dog, Horse

Gene ID URL

6773

Isotype

IgG

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

SNCG Peptide - C-terminal region
MBS3244780-01 0.1 mg

SNCG Peptide - C-terminal region

Ask
View Details
SNCG Peptide - C-terminal region
MBS3244780-02 5x 0.1 mg

SNCG Peptide - C-terminal region

Ask
View Details
SNX29 (RUNDC2A, RUN Domain Containing 2A, FLJ12363, OTTHUMP00000160262) (APC)
207889-APC 100 µL

SNX29 (RUNDC2A, RUN Domain Containing 2A, FLJ12363, OTTHUMP00000160262) (APC)

Ask
View Details
Hsa-miR-3064-3p agomir
HY-R00527A-01 5 nmol

Hsa-miR-3064-3p agomir

Ask
View Details
Hsa-miR-3064-3p agomir
HY-R00527A-02 20 nmol

Hsa-miR-3064-3p agomir

Ask
View Details
Matrilin 3 (MATN3) (NM_002381) Human Tagged ORF Clone
RC221773 10 µg

Matrilin 3 (MATN3) (NM_002381) Human Tagged ORF Clone

Ask
View Details