Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Phospho-Stat2 (Tyr690) Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta) . Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

Synonyms

P113; ISGF-3; STAT113; Signal transducer and activator of transcription 2; STAT2

Gene ID

6773

Swiss Prot

P52630

Modification Site

Tyr690

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Target

Phospho-Stat2 (Tyr690)

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous to that of Tyr689 in Mouse and Tyr690 in Rat.

Prediction Reactivity

Human, Rat, Dog, Horse

Gene ID URL

6773

Isotype

IgG

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

AMHR2 Rabbit monoclonal antibody
E43S41100 100 µL

AMHR2 Rabbit monoclonal antibody

Ask
View Details
Rat histon-H2b ELISA Kit
CN-01735R2 48T

Rat histon-H2b ELISA Kit

Ask
View Details
Rabbit anti PRKAR1A
MBS225155-01 0.05 mL

Rabbit anti PRKAR1A

Ask
View Details
Rabbit anti PRKAR1A
MBS225155-02 5x 0.05 mL

Rabbit anti PRKAR1A

Ask
View Details
C8G siRNA (Mouse)
CRM7958-01 15 nmol

C8G siRNA (Mouse)

Ask
View Details
C8G siRNA (Mouse)
CRM7958-02 30 nmol

C8G siRNA (Mouse)

Ask
View Details