Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Phospho-FoxO3a (Ser253) Polyclonal Antibody, AbBy Fluor™ 594 Conjugated

Product Specifications

Background

Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

Synonyms

FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1; FOXO3

Gene ID

2309

Swiss Prot

O43524

Modification Site

Ser253

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-FoxO3a (Ser253)

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 594

Source

KLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser253

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

590nm/617nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-3140R-BF594

Specificity

This phosphorylation site is homologous to Ser252 in Mouse and Rat.

Prediction Reactivity

Dog, Cow, Sheep, Pig, Horse, Chicken

Gene ID URL

2309

Isotype

IgG

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

CD19 (phospho Tyr531) Polyclonal Antibody
E44H00836 100 µL

CD19 (phospho Tyr531) Polyclonal Antibody

Ask
View Details
CUTA (NM_001014838) Human Untagged Clone
SC319506 10 µg

CUTA (NM_001014838) Human Untagged Clone

Ask
View Details
Mouse Monoclonal CDC5L Antibody (PCRP-CDC5L-2C6) [PerCP]
NBP3-24018PCP 0.1 mL

Mouse Monoclonal CDC5L Antibody (PCRP-CDC5L-2C6) [PerCP]

Ask
View Details
IL4 Antibody
E305410 100 µg - 200 µL

IL4 Antibody

Ask
View Details
PLGA (12K) -PEG-Mal, 2K
HE088022-2K Inquire

PLGA (12K) -PEG-Mal, 2K

Ask
View Details