Phospho-Bcl-2 (Ser70) Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Synonyms
Bcl-2; Apoptosis regulator Bcl-2; Bcl2
Gene ID
24224
Swiss Prot
P49950
Modification Site
Ser70
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Bcl-2 (Ser70)
Clonality
Polyclonal
Conjugation
RBITC
Source
KLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Ser70
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse, Rat, Dog, Rabbit
Gene ID URL
24224
Isotype
IgG
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS280568-01 48 Tests
Human Potassium voltage-gated channel subfamily D member 1 (KCND1) ELISA Kit
Ask
View Details MBS280568-02 96 Tests
Human Potassium voltage-gated channel subfamily D member 1 (KCND1) ELISA Kit
Ask
View Details 
MBS280568-03 5x 96 Tests
Human Potassium voltage-gated channel subfamily D member 1 (KCND1) ELISA Kit
Ask
View Details