SMO Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
Product Specifications
Background
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO) . Required for the accumulation of KIF7 and GLI3 in the cilia.
Synonyms
Gx; SMOH; FZD11; Smoothened homolog; SMO; Protein Gx
Gene ID
6608
Swiss Prot
Q99835
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
551-650/787
Target
SMO
Clonality
Polyclonal
Conjugation
AbBy Fluor™ 488
Source
KLH conjugated synthetic peptide derived from human Smoothened
Applications
WB, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
499nm/519nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Rat, Dog, Cow, Sheep, Horse, Rabbit
Gene ID URL
6608
Isotype
IgG
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