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Claudin 4 Polyclonal Antibody, PE Conjugated

Product Specifications

Background

Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact made up of network of strands that act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.

Synonyms

CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein; CLDN4

Gene ID

1364

Swiss Prot

O14493

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

21-120/209

Target

Claudin 4

Clonality

Polyclonal

Conjugation

PE

Source

KLH conjugated synthetic peptide derived from human CLDN4

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

496,564nm/578nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit

Gene ID URL

1364

Isotype

IgG

Curated Selection

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