Prox1 Polyclonal Antibody, HRP Conjugated
Product Specifications
Background
Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3.
Synonyms
Prospero homeobox protein 1; Homeobox prospero-like protein PROX1; PROX-1; PROX1
Gene ID
5629
Swiss Prot
Q92786
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
151-250/737
Target
Prox1
Clonality
Polyclonal
Conjugation
HRP
Source
KLH conjugated synthetic peptide derived from human Prox-1
Applications
WB, ELISA, IHC-P
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse, Dog, Cow, Pig, Horse, Rabbit
Gene ID URL
5629
Isotype
IgG
Curated Selection
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