CD108 Polyclonal Antibody, AbBy Fluor™ 405 Conjugated

Product Specifications

Background

Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.

Synonyms

JMH; CD108; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1; Semaphorin-7A; JMH blood group antigen; John-Milton-Hargen human blood group Ag; Semaphorin-K1; Sema K1; Semaphorin-L; Sema L; SEMA7A

Gene ID

8482

Swiss Prot

O75326

Cellular Locus

Cell membrane, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human

Immunogen

351-450/666

Target

CD108

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 405

Source

KLH conjugated synthetic peptide derived from human Semaphorin 7A

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

401nm/421nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat, Dog, Cow

Gene ID URL

8482

Isotype

IgG

Curated Selection

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