CLEC5A Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Functions as a positive regulator of osteoclastogenesis. Cell surface receptor that signals via TYROBP. Regulates inflammatory responses. Acts as a key regulator of synovial injury and bone erosion during autoimmune joint inflammation. Critical macrophage receptor for dengue virus serotypes 1-4. The binding of dengue virus to CLEC5A triggers signaling through phosphylation of TYROBP, this interaction does not result in viral entry but stimulates proinflammatory cytokine release.
Synonyms
Mdl1; Ly100; MDL-1; Clecsf5; C-type lectin domain family 5 member A; C-type lectin superfamily member 5; Myeloid DAP12-associating lectin 1; Clec5a
Gene ID
23845
Swiss Prot
Q9R007
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
101-190/190
Target
CLEC5A
Clonality
Polyclonal
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from mouse CLEC5A
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Prediction Reactivity
Cow, Pig, Horse, Rabbit
Gene ID URL
23845
Isotype
IgG
Curated Selection
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