IL21 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG (1) and IgG (3) in B-cells (By similarity) . May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
Synonyms
Za11; IL-21; CVID11; Interleukin-21; IL21
Gene ID
59067
Swiss Prot
Q9HBE4
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human
Immunogen
65-155/155
Target
IL21
Clonality
Polyclonal
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human IL-21
Applications
WB, IF (IHC-P)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Mouse, Rat, Dog, Cow, Pig
Gene ID URL
59067
Isotype
IgG
Curated Selection
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