IL21 Polyclonal Antibody
Product Specifications
Background
Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG (1) and IgG (3) in B-cells (By similarity) . May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
Synonyms
Za11; IL-21; CVID11; Interleukin-21; IL21
Gene ID
59067
Swiss Prot
Q9HBE4
Cellular Locus
Secreted
Host
Rabbit
Cross Reactivity
Human
Immunogen
65-155/155
Target
IL21
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human IL-21
Applications
WB, ELISA, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Rat, Dog, Cow, Pig
Gene ID URL
59067
Isotype
IgG
Curated Selection
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