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IL-17RD Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis.

Synonyms

Interleukin-17 receptor D; IL17RD; DKFZp434N1928; FLJ35755; hSef; IL 17 receptor D; IL 17RD; IL17 receptor D; IL17Rhom; IL17RLM; Interleukin 17 receptor D; Interleukin 17 receptor like protein; Interleukin17 receptor D; MGC133309; SEF; Sef homolog; I17RD_HUMAN.

Gene ID

54756

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

401-500/739

Target

IL-17RD

Clonality

Polyclonal

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human IL-17RD

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat, Dog, Cow, Horse, Chicken, Rabbit

Gene ID URL

54756

Isotype

IgG

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