IL-17RD Polyclonal Antibody
Product Specifications
Background
Feedback inhibitor of fibroblast growth factor mediated Ras-MAPK signaling and ERK activation. May inhibit FGF-induced FGFR1 tyrosine phosphorylation. Regulates the nuclear ERK signaling pathway by spatially blocking nuclear translocation of activated ERK without inhibiting cytoplasmic phosphorylation of ERK. Mediates JNK activation and may be involved in apoptosis.
Synonyms
Interleukin-17 receptor D; IL17RD; DKFZp434N1928; FLJ35755; hSef; IL 17 receptor D; IL 17RD; IL17 receptor D; IL17Rhom; IL17RLM; Interleukin 17 receptor D; Interleukin 17 receptor like protein; Interleukin17 receptor D; MGC133309; SEF; Sef homolog; I17RD_HUMAN.
Gene ID
54756
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
401-500/739
Target
IL-17RD
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human IL-17RD
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Rat, Dog, Cow, Horse, Chicken, Rabbit
Gene ID URL
54756
Isotype
IgG
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