IL12RB1 Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.

Synonyms

CD212; IL-12R[b]; Interleukin-12 receptor subunit beta-1; IL-12 receptor subunit beta-1; IL-12R subunit beta-1; IL-12R-beta-1; IL-12 receptor beta component; Il12rb1; Il12rb

Gene ID

16161

Swiss Prot

Q60837

Cellular Locus

Extracellular, Cell membrane

Host

Rabbit

Cross Reactivity

Mouse

Immunogen

401-500/738

Target

IL12RB1

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from mouse IL-12RB1

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Rat

Gene ID URL

16161

Isotype

IgG

Curated Selection

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