CCL19 Polyclonal Antibody
Product Specifications
Background
Strongly chemotactic for naive (L-selectinhi) CD4 T-cells and for CD8 T-cells and weakly attractive for resting B-cells and memory (L-selectinlo) CD4 T-cells. May play a role in promoting encounters between recirculating T-cells and dendritic cells and in the migration of activated B-cells into the T-zone of secondary lymphoid tissues. Binds to chemokine receptor CCR7. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.
Synonyms
ELC; CKb11; MIP3B; Scya19; exodus-3; C-C motif chemokine 19; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; Small-inducible cytokine A19; Ccl19
Gene ID
24047
Swiss Prot
O70460
Cellular Locus
Extracellular matrix
Host
Rabbit
Immunogen
26-108/108
Target
CCL19
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from mouse CCL19
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Human, Mouse, Rat, Pig
Gene ID URL
24047
Isotype
IgG
Curated Selection
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