PPM1D Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Required for the relief of p53-dependent checkpoint mediated cell cycle arrest. Binds to and dephosphorylates 'Ser-15' of TP53 and 'Ser-345' of CHEK1 which contributes to the functional inactivation of these proteins.

Synonyms

WIP1; PP2C-DELTA; Protein phosphatase 1D; Protein phosphatase 2C isoform delta; Protein phosphatase magnesium-dependent 1 delta; p53-induced protein phosphatase 1; PPM1D

Gene ID

8493

Swiss Prot

O15297

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human

Immunogen

201-300/605

Target

PPM1D

Clonality

Polyclonal

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human PPM1D

Applications

WB, IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Rat, Dog, Cow, Pig, Chicken

Gene ID URL

8493

Isotype

IgG

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