DLK1 Polyclonal Antibody
Product Specifications
Background
This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14) . This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].
Synonyms
DLK; FA1; ZOG; pG2; DLK-1; PREF1; Delta1; Pref-1; Protein delta homolog 1; DLK1
Gene ID
8788
Swiss Prot
P80370
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
251-350/383
Target
DLK1
Clonality
Polyclonal
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from mouse DLK1
Applications
WB, ELISA, FCM, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1ug/ul
Dilution
WB (1:300-5000), ELISA (1:500-1000), FCM (1:20-100), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Prediction Reactivity
Mouse, Rat, Sheep, Pig, Rabbit
Gene ID URL
8788
Isotype
IgG
Curated Selection
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