SIRT1 Polyclonal Antibody, Cy5 Conjugated

Product Specifications

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Synonyms

SIR2; hSIR2; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; SIRT1

Gene ID

23411

Swiss Prot

Q96EB6

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

551-650/747

Target

SIRT1

Clonality

Polyclonal

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human SIRT1

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Dog, Pig, Horse, Rabbit

Gene ID URL

23411

Isotype

IgG

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS3804325-01 48 Well

Human Glucosidase ELISA Kit

Ask

View Details

MBS3804325-02 96 Well

Human Glucosidase ELISA Kit

Ask

View Details

MBS3804325-03 5x 96 Well

Human Glucosidase ELISA Kit

Ask

View Details

MBS3804325-04 10x 96 Well

Human Glucosidase ELISA Kit

Ask

View Details

036516-Biotin 200 µL

HERPUD1, NT (HERPUD1, HERP, KIAA0025, MIF1, Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein, Methyl methanesulfonate (MMF) -inducible fragment protein 1) (Biotin) discontinued

Ask

View Details

20465015 1.0 µg DNA

Fetub ORF Vector (Mouse) (pORF)

Ask

View Details