PSD95 Polyclonal Antibody, FITC Conjugated
Product Specifications
Background
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity) .
Synonyms
Disks large homolog 4; DLG4; Postsynaptic density protein 95; PSD-95; Synapse-associated protein 90; SAP-90; SAP90
Gene ID
1742
Swiss Prot
P78352
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Mouse, Rat
Immunogen
351-450/724
Target
PSD95
Clonality
Polyclonal
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human DLG4
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Human, Dog, Cow, Sheep, Pig, Horse, Rabbit
Gene ID URL
1742
Isotype
IgG
Curated Selection
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