CD33 Polyclonal Antibody, RBITC Conjugated
Product Specifications
Background
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase (s) via their SH2 domain (s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) .
Synonyms
P67; SIGLEC3; SIGLEC-3; Myeloid cell surface antigen CD33; Sialic acid-binding Ig-like lectin 3; gp67; CD33
Gene ID
945
Swiss Prot
P20138
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
261-364/364
Target
CD33
Clonality
Polyclonal
Conjugation
RBITC
Source
KLH conjugated synthetic peptide derived from human CD33
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
570nm/595nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
945
Isotype
IgG
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
044173-HRP 200 µL
ZNF276, ID (ZNF276, ZFP276, ZNF477, Zinc finger protein 276, Zinc finger protein 477) (Azide free) (HRP) discontinued
Sign In for Pricing
View Details 
302811-ML650 100 µL
TRIM55 (Tripartite Motif-Containing Protein 55, Muscle-specific RING Finger Protein 2, MuRF-2, MuRF2, RING Finger Protein 29, TRIM55, MURF2, RNF29) (MaxLight 650) discontinued
Sign In for Pricing
View Details 