Thrombomodulin Polyclonal Antibody, AbBy Fluor™ 555 Conjugated

Product Specifications

Background

Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca) . Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.

Synonyms

Thrombomodulin; CD 141; CD141; CD141 antigen; Fetomodulin; THBD; THRM; TM; AHUS 6; AHUS6; BDCA 3; BDCA3; THPH12; TRBM_HUMAN

Gene ID

7056

Swiss Prot

P07204

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

21-120/575

Target

Thrombomodulin

Clonality

Polyclonal

Conjugation

AbBy Fluor™ 555

Source

KLH conjugated synthetic peptide derived from human Thrombomodulin

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

553nm/568nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Mouse, Dog, Cow, Sheep

Gene ID URL

7056

Isotype

IgG

Curated Selection

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