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KLK7 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

May catalyze the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. Cleaves insulin A chain at '14-Tyr-|-Gln-15' and insulin B chain at '6-Leu-|-Cys-7', '16-Tyr-|-Leu-17', '25-Phe-|-Tyr-26' and '26-Tyr-|-Thr-27'. Could play a role in the activation of precursors to inflammatory cytokines.

Synonyms

HK7; SCCE; PRSS6; Kallikrein-7; Serine protease 6; Stratum corneum chymotryptic enzyme; hSCCE; KLK7

Gene ID

5650

Swiss Prot

P49862

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Rat

Target

KLK7

Clonality

Polyclonal

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human KLK7

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1ug/ul

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Human, Mouse, Dog, Cow, Pig

Gene ID URL

5650

Isotype

IgG

Curated Selection

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