TLR1 Polyclonal Antibody, APC Conjugated
Product Specifications
Background
Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) .
Synonyms
TIL; CD281; rsc786; TIL. LPRS5; Toll-like receptor 1; Toll/interleukin-1 receptor-like protein; TLR1; KIAA12
Gene ID
7096
Swiss Prot
Q15399
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Immunogen
101-200/786
Target
TLR1
Clonality
Polyclonal
Conjugation
APC
Source
KLH conjugated synthetic peptide derived from human TLR1
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/660nm
Concentration
1ug/ul
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Dog, Cow, Horse
Gene ID URL
7096
Isotype
IgG
Curated Selection
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