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TLR1 Polyclonal Antibody, Cy7 Conjugated

Product Specifications

Background

Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity) .

Synonyms

TIL; CD281; rsc786; TIL. LPRS5; Toll-like receptor 1; Toll/interleukin-1 receptor-like protein; TLR1; KIAA12

Gene ID

7096

Swiss Prot

Q15399

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

101-200/786

Target

TLR1

Clonality

Polyclonal

Conjugation

Cy7

Source

KLH conjugated synthetic peptide derived from human TLR1

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

743nm/767nm

Concentration

1ug/ul

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Prediction Reactivity

Dog, Cow, Horse

Gene ID URL

7096

Isotype

IgG

Curated Selection

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