TGM3 Polyclonal Antibody, PerCP Conjugated
Product Specifications
Background
Catalyzes the calcium-dependent formation of isopeptide cross-links between glutamine and lysine residues in various proteins, as well as the conjugation of polyamines to proteins. Involved in the formation of the cornified envelope (CE), a specialized component consisting of covalent cross-links of proteins beneath the plasma membrane of terminally differentiated keratinocytes. Catalyzes small proline-rich proteins (SPRR1 and SPRR2) and LOR cross-linking to form small interchain oligomers, which are further cross-linked by TGM1 onto the growing CE scaffold (By similarity) . In hair follicles, involved in cross-linking structural proteins to hardening the inner root sheath.
Synonyms
TGE; Protein-glutamine gamma-glutamyltransferase E; Transglutaminase E; TG (E) ; TGase E; Transglutaminase-3; TGase-3; TGM3
Gene ID
7053
Swiss Prot
Q08188
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Mouse
Immunogen
601-693/693
Target
TGM3
Clonality
Polyclonal
Conjugation
PerCP
Source
KLH conjugated synthetic peptide derived from human TGM3
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
482nm/677nm
Concentration
1ug/ul
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Prediction Reactivity
Human, Rat, Dog, Cow, Horse, Rabbit
Gene ID URL
7053
Isotype
IgG
Curated Selection
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