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TMEM175 Polyclonal Antibody

Product Specifications

Background

Organelle-specific potassium channel specifically responsible for potassium conductance in endosomes and lysosomes. Forms a potassium-permeable leak-like channel, which regulates lumenal pH stability and is required for autophagosome-lysosome fusion. Constitutes the major lysosomal potassium channel.

Synonyms

MGC4618; Hypothetical protein DKFZp547K246; hypothetical protein LOC84286; Hypothetical protein MGC4618; TM175_HUMAN; tmem175; Transmembrane protein 175.

Gene ID

84286

Swiss Prot

Q9BSA9

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Mouse, Rat

Immunogen

231-330/504

Target

TMEM175

Clonality

Polyclonal

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human TM175

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1ug/ul

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Prediction Reactivity

Human

Gene ID URL

84286

Isotype

IgG

Curated Selection

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